cephalexin   Click here for help

GtoPdb Ligand ID: 4832

Synonyms: cefalexin | Ceporex® | Keflex®
Approved drug
cephalexin is an approved drug (FDA (1971, prior history not available))
Compound class: Synthetic organic
Comment: Cephalexin is a cephalosporin antibiotic.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 138.03
Molecular weight 347.09
XLogP -2.19
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES NC(c1ccccc1)C(=O)NC1C(=O)N2C1SCC(=C2C(=O)O)C
Isomeric SMILES N[C@H](c1ccccc1)C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C
InChI InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
InChI Key ZAIPMKNFIOOWCQ-UEKVPHQBSA-N
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Summary of Clinical Use Click here for help
Cephalexin is used to treat bacterial infections.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
Cephalexin inhibits bacterial cell wall synthesis resulting in bacterial cell lysis and death.