Synonyms: methofadin | sulfamethomidine
Compound class:
Synthetic organic
Comment: Sulfametomidine is a sulfonamide antibacterial compound.
|
|
No information available. |
Summary of Clinical Use |
The pharmacokinetics of sulfametomidine have been studied [5] and it progressed to clinical trial as a treatment for urinary tract infections [3]. |
Mechanism Of Action and Pharmacodynamic Effects |
Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants [2]. The antibacterial MMOA is competitive inhibition of bacterial dihydropteroate synthase (DHPS) resulting in a block of folate biosynthesis [1]. |