FSH

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Ligands
FSH (Human)

GtoPdb Ligand ID: 1157

Synonyms: follitropin | human follicle stimulating hormone

FSH is an approved drug (FDA (1997))

Compound class: Endogenous peptide in human, mouse or rat

Comment: FSH is a 35.5 kDa glycoprotein heterodimer, consisting of an alpha (CGA) and a beta polypeptide (FSHB) subunit. This entry also represents urofollitropin, which is a purified form of FSH that is extracted from human menopausal urine.

Species: Human

View more information in the IUPHAR Pharmacology Education Project: fsh

Summary
Biological activity
Clinical data
Structure
Similar ligands
(Un)labelled forms

No information available.

No information available.

Summary of Clinical Use
Urofollitropin/FSH is used to treat female infertility.

Summary of Clinical Use

Urofollitropin/FSH is used to treat female infertility.

Mechanism Of Action and Pharmacodynamic Effects
Downstream signals, resulting from FSH-induced activation of the follicle stimulating hormone receptor, stimulate recruitment and development of ovarian follicles.

Mechanism Of Action and Pharmacodynamic Effects

Downstream signals, resulting from FSH-induced activation of the follicle stimulating hormone receptor, stimulate recruitment and development of ovarian follicles.