FSH   Click here for help

GtoPdb Ligand ID: 1157

Synonyms: follitropin | human follicle stimulating hormone
Approved drug
FSH is an approved drug (FDA (1997))
Comment: FSH is a 35.5 kDa glycoprotein heterodimer, consisting of an alpha (CGA) and a beta polypeptide (FSHB) subunit. This entry also represents urofollitropin, which is a purified form of FSH that is extracted from human menopausal urine.
Species: Human
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Summary of Clinical Use Click here for help
Urofollitropin/FSH is used to treat female infertility.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
Downstream signals, resulting from FSH-induced activation of the follicle stimulating hormone receptor, stimulate recruitment and development of ovarian follicles.