Ligand id: 865

Name: GW-5823

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 98.84
Molecular weight 587.25
XLogP 5.45
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCK1 receptor Hs Agonist Full agonist 7.6 pIC50 - 1
pIC50 7.6 (IC50 2.51x10-8 M) [1]
CCK2 receptor Hs Antagonist Antagonist 6.0 pIC50 - 1
pIC50 6.0 [1]