CCL4   Click here for help

GtoPdb Ligand ID: 757

Synonyms: HC21 | macrophage inflammatory protein-1β | MIP-1β
Immunopharmacology Ligand
Comment: CCL4 is a CC family chemokine more commonly referred to as macrophage inflammatory protein-1β or MIP-1β. It acts in a dimer with CCL3 (MIP-1α) [1].
Species: Human
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Natural/Endogenous Targets
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCR5 Ligand is endogenous in the given species Hs Agonist Full agonist 9.4 – 9.6 pKi - 6,8
pKi 9.4 – 9.6 [6,8]
CCR1 Ligand is endogenous in the given species Hs Antagonist Antagonist 7.1 – 7.8 pKi - 3,5
pKi 7.1 – 7.8 [3,5]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference