Ligand id: 6761

Name: CCG-1423

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 9
Topological polar surface area 67.43
Molecular weight 454.05
XLogP 5.32
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Bioactivity Comments
CCG-1423 inhibits Rho-dependent invasion by PC-3 prostate cancer cells. It acts downstream of Rho and shows specificity for SRE.L-mediated transcription [1].