IL-9   Click here for help

GtoPdb Ligand ID: 5000

Synonyms: interleukin-9
Immunopharmacology Ligand
Comment: IL-9 is a pleiotropic cytokine. Th9 cells and/or the IL-9/IL-9 receptor pathway are potential targets for pharmacological intervention in atopic diseases such as asthma and ulcerative colitis.
Species: Human
Natural/Endogenous Targets
Target
Interleukin-9 receptor
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-9 receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
enokizumab Peptide Primary target of this compound Hs Antibody Binding 11.2 pKd - 2
pKd 11.2 (Kd 6x10-12 M) [2]