Synonyms: aldesleukin | interleukin-2 | Proleukin®
IL-2 is an approved drug (FDA (1992))
Compound class:
Endogenous peptide in human, mouse or rat
Comment: IL-2 and IL-15 are cytokines that share common biological effects, but also exhibit distinct, and sometimes competing, functions [6]. Recombinant IL-2 is used clinically with the generic name aldesleukin.
Abbas et al. (2018) have written a review of IL-2 biology and the progress that has been made in developing IL-2 therapeutics [1].
Species: Human
View more information in the IUPHAR Pharmacology Education Project: interleukin-2 |
Natural/Endogenous Targets | ||
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Selectivity at catalytic receptors | ||||||||||||||||||||||||||||||||||
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Other ligands which bind to or alter the activity of this ligand | ||||||||||||||||||||||||||||||||||||||||||||||
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