BMP-10   Click here for help

GtoPdb Ligand ID: 4875

Comment: The active peptide is a disulphide bond-linked homodimer
Species: Human
Natural/Endogenous Targets
Target
Bone morphogenetic protein receptors
Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Bone morphogenetic protein receptors Ligand is endogenous in the given species Hs Agonist Agonist - - -
Other ligands which bind to or alter the activity of this ligand
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Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
luspatercept Peptide Approved drug Hs Fusion protein Binding 10.1 pKd - 1
pKd 10.1 (Kd 8.7x10-11 M) [1]
Description: Binding to BMP10 determined by surface plasmon resonance (SPR).