[125I]PD142308

Ligand id: 3472

Name: [125I]PD142308    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 5
Rotatable bonds 13
Topological polar surface area 146.54
Molecular weight 698.2
XLogP 5.7
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCK2 receptor Cp Antagonist Antagonist 9.6 pKd - 1
pKd 9.6 (Kd 2.5x10-10 M) [1]