lanosterol

Ligand id: 2746

Name: lanosterol

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 20.23
Molecular weight 426.39
XLogP 10.21
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
Farnesoid X receptor-β
Enzymes Catalysing Reactions with this Compound as a Substrate or Product
Enzyme EC number Reaction Reference
lanosterol synthase
Selectivity at nuclear hormone receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Farnesoid X receptor-β Mm Agonist Agonist 6.0 pEC50 - 2
pEC50 6.0 [2]
Targets where the ligand is described in the comment field
Target Comment