Synonyms: compound 44 [PMID: 37647546] | ERD3111
Compound class:
Synthetic organic
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Bioactivity Comments |
In vitro ER α DC50 of ERD-3111 is 0.5 nM, with a maximum degradation of 91%. ERD-3111 efficiently degrades wild-type and mutated ERα proteins in tumour tissues, and promotes tumour regression in xenograft models with wild-type or mutated ER [1]. |