Synonyms: CAD-1883 | CAD1883 | compound 1 [US9975886B1]
Compound class:
Synthetic organic
Comment: Rimtuzalcap (CAD-1883) is a KCa2 channel activator (positive allosteric modulator) [1], that was developed for potential to treat movement disorders such as essential tremor and spinocerebellar ataxia.
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Bioactivity Comments |
In vitro (whole-cell patch-clamp assay), a concentration of 400 nM of rimtuzalcap increases KCa2.2 channel basal current by 100% [1]. |
Selectivity at ion channels | ||||||||||||||||||||||||||||||||||
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