Synonyms: Stachybotrys microspora triprenyl phenol 7 | BIIB131 | orniplabin | SMTP7 | TMS-007
Compound class:
Synthetic organic
Comment: SMTP-7 is a natural triprenyl phenol that's produced by Stachybotrys microspora (a fungus) [2]. It is a complex molecule with 5 chiral centers whose absolute stereochemical configuration has been determined using microcrystal electron diffraction (MicroED) [6]. SMTP-7 produces thrombolytic [4], anti-inflammatory, and antioxidant effects. It is being considered as a clinical anti-thrombotic agent for use in stroke patients [5]. The compound has activity as a plasminogen modulator and soluble epoxide hydrolase inhibitor that may offer a novel therapeutic intervention for cardiometabolic diseases [1].
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