Synonyms: EHT-1864 | EHT1864
Compound class:
Synthetic organic
Comment: Potent Rac family inhibitor. Marketed as EHT 1864 dihydrochloride.
|
|
Bioactivity Comments |
Inhibitor of Rac family GTPases. Blocks activation by direct binding to Rac1, Rac1b, Rac2 and Rac3 (Kd values are 40, 50, 60 and 250 nM respectively) [1-2]. |
Selectivity at ligand targets | ||||||||||||||||||||||||||||||||||
Key to terms and symbols | Click column headers to sort | |||||||||||||||||||||||||||||||||
|