- Guide to PHARMACOLOGY
Compound class: Synthetic organic
Comment: AN13762 is a preclinical antimalarial candidate optimized from the benzoxaboroles, a novel class of boron-containing compound .
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|The interaction table below provides data from an evaluation of the antimalarial (asexual blood stage) activity of AN13762, using a panel of culture-adapted P. falciparum strains, with no evidence of reduced potency against drug resistant strains being observed.|
|Whole organism assay data|
|Key to terms and symbols||Click on species/strain names for details||Click column headers to sort|