- Guide to PHARMACOLOGY
Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|Ligand families/groups||Antimalarial ligands|
|WHO Essential Medicine||WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.|
|International Nonproprietary Names|
|Artesunate is a semisynthetic derivative of artemisinin, a natural product isolated from the qinghao or sweet wormwood plant (Artemisia annua). It contains an unusual endoperoxide bridge, believed to be responsible for the antimalarial activity of artemisinin and its derivatives.
Artesunate is a prodrug that is converted to the active metabolite artenimol (dihydroartemisinin).
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
|CAS Registry No.||88495-63-0 (source: Scifinder)|
|GtoPdb PubChem SID||374883843|
|RCSB PDB Ligand||D95|
|Search Google for chemical match using the InChIKey||FIHJKUPKCHIPAT-AHIGJZGOSA-N|
|Search Google for chemicals with the same backbone||FIHJKUPKCHIPAT|
|Search PubMed clinical trials||artesunate|
|Search PubMed titles||artesunate|
|Search PubMed titles/abstracts||artesunate|
|Search UniChem for chemical match using the InChIKey||FIHJKUPKCHIPAT-AHIGJZGOSA-N|
|Search UniChem for chemicals with the same backbone||FIHJKUPKCHIPAT|
Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.
Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.✖
Cat. No. 6827