- Guide to PHARMACOLOGY
Molecular properties generated using the CDK
|Compound class||Natural product or derivative|
|Ligand families/groups||Antimalarial ligands|
|International Nonproprietary Names|
|Artemisinin is a sesquiterpene lactone with an unusual endoperoxide bridge, believed to be responsible for the antimalarial activity of the compound. It is a natural product, isolated from the qinghao or sweet wormwood plant (Artemisia annua) and used in Chinese traditional medicine to treat fever.
Artemisinin is a prodrug that is converted to the active metabolite artenimol (dihydroartemisinin).
We show one representation of artemisinin here. As with other natural products, there are alternative chemical structures due to the complex stereochemistry.
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
|CAS Registry No.||63968-64-9 (source: Scifinder)|
|GtoPdb PubChem SID||374883841|
|Search Google for chemical match using the InChIKey||BLUAFEHZUWYNDE-NNWCWBAJSA-N|
|Search Google for chemicals with the same backbone||BLUAFEHZUWYNDE|
|Search PubMed clinical trials||artemisinin|
|Search PubMed titles||artemisinin|
|Search PubMed titles/abstracts||artemisinin|
|Search UniChem for chemical match using the InChIKey||BLUAFEHZUWYNDE-NNWCWBAJSA-N|
|Search UniChem for chemicals with the same backbone||BLUAFEHZUWYNDE|
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Cat. No. 2668