amfenac   Click here for help

GtoPdb Ligand ID: 7565

Synonyms: AHR-5850D | Fenazox® (Japan)
Approved drug
amfenac is an approved drug
Compound class: Synthetic organic
Comment: Amfenac is the active metabolite of nepafenac. It is a potent non-steroidal antiinflammatory drug (NSAID) [2].
Marketed formulations may contain amfenac sodium (PubChem CID 23665728).
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 80.39
Molecular weight 255.09
XLogP 2.62
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES OC(=O)Cc1cccc(c1N)C(=O)c1ccccc1
Isomeric SMILES OC(=O)Cc1cccc(c1N)C(=O)c1ccccc1
InChI InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18)
Classification Click here for help
Compound class Synthetic organic
Ligand families/groups Non-steroidal anti-inflammatory ligands
Approved drug? Yes
Prodrug nepafenac
IUPAC Name Click here for help
2-[2-amino-3-(benzoyl)phenyl]acetic acid
International Nonproprietary Names Click here for help
INN number INN
4363 amfenac
Synonyms Click here for help
AHR-5850D | Fenazox® (Japan)
Database Links Click here for help
CAS Registry No. 51579-82-9
ChEMBL Ligand CHEMBL25146
GtoPdb PubChem SID 223365901
PubChem CID 2136
Search Google for chemical match using the InChIKey SOYCMDCMZDHQFP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SOYCMDCMZDHQFP
Search PubMed clinical trials amfenac
Search PubMed titles amfenac
Search PubMed titles/abstracts amfenac
UniChem Compound Search for chemical match using the InChIKey SOYCMDCMZDHQFP-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey SOYCMDCMZDHQFP-UHFFFAOYSA-N
Wikipedia Amfenac