lenalidomide   Click here for help

GtoPdb Ligand ID: 7331

Synonyms: CC-5013 | CDC-501 | Revlimid®
Approved drug Immunopharmacology Ligand
lenalidomide is an approved drug (FDA (2005), EMA (2007))
Compound class: Synthetic organic
Comment: Lenalidomide is a derivative of thalidomide with anti-inflammatory and anti-cancer actions.
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 95.99
Molecular weight 259.1
XLogP 0.22
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES OC1=NC(=O)C(CC1)N1Cc2c(C1=O)cccc2N
Isomeric SMILES OC1=NC(=O)C(CC1)N1Cc2c(C1=O)cccc2N
InChI InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
Classification Click here for help
Compound class Synthetic organic
Ligand families/groups PROTACs, molecular glues and other degraders
Approved drug? Yes (FDA (2005), EMA (2007))
WHO Essential Medicine WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
Click to view more information about the WHO Model Lists of Essential Medicines.
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
8505 lenalidomide
Synonyms Click here for help
CC-5013 | CDC-501 | Revlimid®
Database Links Click here for help
Specialist databases
Reactome Drug Reactome logo R-ALL-9681174
Reactome Reaction Reactome logo R-HSA-9681169
Other databases
CAS Registry No. 191732-72-6
DrugBank Ligand DB00480
DrugCentral Ligand 3317
GtoPdb PubChem SID 178103903
PubChem CID 216326
Search Google for chemical match using the InChIKey GOTYRUGSSMKFNF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GOTYRUGSSMKFNF
Search PubMed clinical trials lenalidomide
Search PubMed titles lenalidomide
Search PubMed titles/abstracts lenalidomide
UniChem Compound Search for chemical match using the InChIKey GOTYRUGSSMKFNF-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey GOTYRUGSSMKFNF-UHFFFAOYSA-N
Wikipedia Lenalidomide

Product suppliers

View disclaimer

Lenalidomide (links to external site)
Cat. No. 6305