ziprasidone   Click here for help

GtoPdb Ligand ID: 59

Synonyms: CP-88059 | CP-88059-27 | CP-880591 | CP-8805927 | Geodon®
Approved drug
ziprasidone is an approved drug (FDA (2001))
Compound class: Synthetic organic
Comment: Ziprasidone is a monoaminergic antagonist with affinity for a range of receptors including dopamine receptors, alpha 1 and 2 adrenoceptors, the histamine H1 receptor, and serotonin 5-HT receptors. Marketed formulations may contain ziprasidone hydrochloride (PubChem CID 219099).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 76.71
Molecular weight 412.11
XLogP 3.89
No. Lipinski's rules broken 0
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Canonical SMILES O=C1Nc2c(C1)cc(c(c2)Cl)CCN1CCN(CC1)c1nsc2c1cccc2
Isomeric SMILES O=C1Nc2c(C1)cc(c(c2)Cl)CCN1CCN(CC1)c1nsc2c1cccc2
InChI InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2001))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
7155 ziprasidone
Synonyms Click here for help
CP-88059 | CP-88059-27 | CP-880591 | CP-8805927 | Geodon®
Database Links Click here for help
Specialist databases
GPCRdb Ligand ziprasidone
Other databases
BindingDB Ligand 50048803
CAS Registry No. 146939-27-7
DrugBank Ligand DB00246
DrugCentral Ligand 2865
GtoPdb PubChem SID 135651359
PubChem CID 60854
Search Google for chemical match using the InChIKey MVWVFYHBGMAFLY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MVWVFYHBGMAFLY
Search PubMed clinical trials ziprasidone
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UniChem Compound Search for chemical match using the InChIKey MVWVFYHBGMAFLY-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey MVWVFYHBGMAFLY-UHFFFAOYSA-N
Wikipedia Ziprasidone