ziprasidone   Click here for help

GtoPdb Ligand ID: 59

Synonyms: CP-88059 | CP-88059-27 | CP-880591 | CP-8805927 | Geodon®
Approved drug
ziprasidone is an approved drug (FDA (2001))
Compound class: Synthetic organic
Comment: Ziprasidone is a monoaminergic antagonist with affinity for a range of receptors including dopamine receptors, alpha 1 and 2 adrenoceptors, the histamine H1 receptor, and serotonin 5-HT receptors. Marketed formulations may contain ziprasidone hydrochloride (PubChem CID 219099).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 76.71
Molecular weight 412.11
XLogP 3.89
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES O=C1Nc2c(C1)cc(c(c2)Cl)CCN1CCN(CC1)c1nsc2c1cccc2
Isomeric SMILES O=C1Nc2c(C1)cc(c(c2)Cl)CCN1CCN(CC1)c1nsc2c1cccc2
InChI InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)
InChI Key MVWVFYHBGMAFLY-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2001))
IUPAC Name Click here for help
5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one
International Nonproprietary Names Click here for help
INN number INN
7155 ziprasidone
Synonyms Click here for help
CP-88059 | CP-88059-27 | CP-880591 | CP-8805927 | Geodon®
Database Links Click here for help
BindingDB Ligand 50048803
CAS Registry No. 146939-27-7
ChEBI CHEBI:10119
ChEMBL Ligand CHEMBL708
DrugBank Ligand DB00246
DrugCentral Ligand 2865
GtoPdb PubChem SID 135651359
PubChem CID 60854
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Wikipedia Ziprasidone