Natural/Endogenous Targets
Target CD27

Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference CD27 Hs None - - - - ⤷

Other ligands which bind to or alter the activity of this ligand
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Ligand Sp. Type Action Value Parameter Concentration range (M) Reference cusatuzumab Hs Antibody Binding 10.7 pKd - 2 ⤷ pKd 10.7 (Kd 1.9x10-11 M) [2] Description: Equilibrium dissociation constant determined by surface plasmon resonance analysis using a hCD70-coated sensor chip. balertatug Hs Antibody Binding 9.2 – 9.4 pKd - 1 ⤷ pKd 9.4 (Kd 3.7x10-10 M) [1] Description: Binding affinity of Europium-labeled antibody h1F6 HJLA to CD70 positive Caki-2 cells pKd 9.2 (Kd 6.8x10-10 M) [1] Description: Binding affinity of Europium-labeled antibody h1F6 HJLA to CD70 positive ACHN cells