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CD70   Click here for help

GtoPdb Ligand ID: 5079

Synonyms: CD27 ligand | Ki-24 | TNFSF7
Compound class: Endogenous peptide in human, mouse or rat
Species: Human
Natural/Endogenous Targets
Target
CD27
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD27 Ligand is endogenous in the given species Hs None - - - -
⤷
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
cusatuzumab Peptide Hs Antibody Binding 10.7 pKd - 2
⤷ pKd 10.7 (Kd 1.9x10-11 M) [2]
Description: Equilibrium dissociation constant determined by surface plasmon resonance analysis using a hCD70-coated sensor chip.
balertatug Peptide Hs Antibody Binding 9.2 – 9.4 pKd - 1
⤷ pKd 9.4 (Kd 3.7x10-10 M) [1]
Description: Binding affinity of Europium-labeled antibody h1F6 HJLA to CD70 positive Caki-2 cells
pKd 9.2 (Kd 6.8x10-10 M) [1]
Description: Binding affinity of Europium-labeled antibody h1F6 HJLA to CD70 positive ACHN cells