- Guide to PHARMACOLOGY
Synonyms: aldesleukin | interleukin-2 | Proleukin®
IL-2 is an approved drug (FDA (1992))
Compound class: Endogenous peptide in human, mouse or rat
Comment: IL-2 and IL-15 are cytokines that share common biological effects, but also exhibit distinct, and sometimes competing, functions . Recombinant IL-2 is used clinically with the generic name aldesleukin.
Abbas et al. (2018) have written a review of IL-2 biology and the progress that has been made in developing IL-2 therapeutics .
View more information in the IUPHAR Pharmacology Education Project: interleukin-2
|Compound class||Endogenous peptide in human, mouse or rat|
|Approved drug?||Yes (FDA (1992))|
|aldesleukin | interleukin-2 | Proleukin®|
|Ensembl Gene||ENSG00000109471 (Hs)|
|GtoPdb PubChem SID||178101682|
|Human Protein Atlas||ENSG00000109471 (Hs)|