Synonyms: MRS 1220 | MRS-1220
Compound class:
Synthetic organic
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Jacobson KA, Park KS, Jiang JL, Kim YC, Olah ME, Stiles GL, Ji XD. (1997)
Pharmacological characterization of novel A3 adenosine receptor-selective antagonists. Neuropharmacology, 36 (9): 1157-65. [PMID:9364471] |
2. Kim YC, Ji XD, Jacobson KA. (1996)
Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype. J Med Chem, 39 (21): 4142-8. [PMID:8863790] |
3. Stewart M, Steinig AG, Ma C, Song JP, McKibben B, Castelhano AL, MacLennan SJ. (2004)
[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors. Biochem Pharmacol, 68 (2): 305-12. [PMID:15194002] |
4. Sullivan GW, Rieger JM, Scheld WM, Macdonald TL, Linden J. (2001)
Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists. Br J Pharmacol, 132 (5): 1017-26. [PMID:11226132] |
5. Yates L, Clark JH, Martin TJ, James S, Broadley KJ, Kidd EJ. (2006)
Radioligand binding and functional responses of ligands for human recombinant adenosine A(3) receptors. Auton Autacoid Pharmacol, 26 (2): 191-200. [PMID:16553647] |