ruthenium red   Click here for help

GtoPdb Ligand ID: 2432

Synonyms: ammoniated ruthenium oxychloride
Compound class: Inorganic
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
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A capsaicin-receptor homologue with a high threshold for noxious heat.
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Heat-evoked activation of the ion channel, TRPV4.
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Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.
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8. Nilius B, Prenen J, Vennekens R, Hoenderop JG, Bindels RJ, Droogmans G. (2001)
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9. Peier AM, Reeve AJ, Andersson DA, Moqrich A, Earley TJ, Hergarden AC, Story GM, Colley S, Hogenesch JB, McIntyre P et al.. (2002)
A heat-sensitive TRP channel expressed in keratinocytes.
Science, 296 (5575): 2046-9. [PMID:12016205]
10. Voets T, Nilius B, Hoefs S, van der Kemp AW, Droogmans G, Bindels RJ, Hoenderop JG. (2004)
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.
J Biol Chem, 279 (1): 19-25. [PMID:14576148]
11. Watanabe H, Davis JB, Smart D, Jerman JC, Smith GD, Hayes P, Vriens J, Cairns W, Wissenbach U, Prenen J et al.. (2002)
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