tozorakimab 
GtoPdb Ligand ID: 12964
|
Synonyms: MEDI-3506 | MEDI3506
Compound class:
Antibody
Comment: Tozorakimab (MEDI3506) is a high-affinity anti-IL-33 monoclonal antibody. It inhibits IL-33-induced signalling to produce an anti-inflammatory effect [2]. Tozorakimab blocks the actions of both reduced IL-33 (IL-33red) and oxidized IL-33 (IL-33ox) metabolites through their respective downstream pathways (ST2 for IL-33red, RAGE/EGFR complex for IL-33ox) [1,3-4].
|
Classification  |
|
| Compound class | Antibody |
| International Nonproprietary Names |
|
| INN number | INN |
| 11647 | tozorakimab |
| Synonyms |
| MEDI-3506 | MEDI3506 |
| Database Links |
|
| Specialist databases | |
| IMGT/mAb-DB | 1149 |
| Other databases | |
| GtoPdb PubChem SID | 485206085 |
| Search PubMed clinical trials | tozorakimab |
| Search PubMed titles | tozorakimab |
| Search PubMed titles/abstracts | tozorakimab |
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License