spexin-1   Click here for help

GtoPdb Ligand ID: 11417

Compound class: Endogenous peptide in human, mouse or rat
Comment: Spexin-1 has been identified as an agonist of galanin receptors GALR2 and GALR3 [1-2]. It is a cleavage product of the 116 amino acid spexin precursor which is cleaved into two chains: spexin-1 and spexin-2 (FISDQSRRKDLSDRPLPE).
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
SPX spexin hormone Human spexin precursor C12orf39, neuropeptide Q (NPQ)
Database Links Click here for help
Specialist databases
GPCRdb Ligand spexin-1
Other databases
Ensembl Gene ENSG00000134548 (Hs)
Entrez Gene 80763 (Hs)
GtoPdb PubChem SID 440816786
Human Protein Atlas ENSG00000134548 (Hs)
RefSeq Nucleotide NM_030572 (Hs)
RefSeq Protein NP_085049 (Hs)
UniProtKB Q9BT56 (Hs)