lincomycin

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Ligands
lincomycin

GtoPdb Ligand ID: 10941

Synonyms: Bactramycin® | L-Mycin® | LCM | Lincocin® | Lincorex® | U 10,149A | U-10149

lincomycin is an approved drug (FDA (1964))

Comment: Lincomycin is a lincosamide antibacterial that has activity against Gram-positive and anaerobic bacteria [2]. It was isolated from the actinomycete Streptomyces lincolnensis. Pathogenic species of bacteria that are sensitive to lincomycin include Streptococcus, Staphylococcus, and Mycoplasma.

lincomycin is commercially available from our sponsors

2D Structure

Physico-chemical Properties

Hydrogen bond acceptors	8
Hydrogen bond donors	5
Rotatable bonds	8
Topological polar surface area	147.79
Molecular weight	406.21
XLogP	0.69
No. Lipinski's rules broken	0

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

SMILES / InChI / InChIKey

Canonical SMILES	CCC[C@@H]1C[C@@H](C(=O)N[C@H]([C@@H](C)O)[C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)N(C)C1
Isomeric SMILES	CCC[C@H]1CN([C@@H](C1)C(=O)N[C@@H]([C@H]2O[C@H](SC)[C@@H]([C@H]([C@H]2O)O)O)[C@H](O)C)C
InChI	InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1
InChI Key	OJMMVQQUTAEWLP-KIDUDLJLSA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)