- Guide to PHARMACOLOGY
Compound class: Synthetic organic
Comment: Compound 49c is a hydroxyl-ethyl-amine-based scaffold compound with antimalarial activity . We have drawn the structure as depicted in Pino et al. (2017) , with the indicated stereochemistry (but note that the IUPAC they provide is for the flat structure that is represented by PubChem CID 11619556).
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|Ligand families/groups||Antimalarial ligands|
|GtoPdb PubChem SID||385612178|
|Search Google for chemical match using the InChIKey||NCNJHAHPOUUEQX-LDVROUIZSA-N|
|Search Google for chemicals with the same backbone||NCNJHAHPOUUEQX|
|UniChem Compound Search for chemical match using the InChIKey||NCNJHAHPOUUEQX-LDVROUIZSA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||NCNJHAHPOUUEQX-LDVROUIZSA-N|