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Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 37 | 2752 | 18p11.22-p11.21 | PIEZO2 | piezo type mechanosensitive ion channel component 2 | |
Mouse | 37 | 2822 | 18 E1 | Piezo2 | piezo-type mechanosensitive ion channel component 2 | |
Rat | - | 2720 | 18q12.1 | Piezo2 | piezo-type mechanosensitive ion channel component 2 | |
Gene and Protein Information Comments | ||||||
Piezo proteins have between 24 and 36 predicted transmembrane domains. |
Previous and Unofficial Names |
DA3 | DA5 | DAIPT | FAM38B | FAM38B2 | HsT748 | HsT771 | MWKS |
Database Links | |
Alphafold | Q9H5I5 (Hs), Q8CD54 (Mm) |
CATH/Gene3D | 1.25.10.10 |
Ensembl Gene | ENSG00000154864 (Hs), ENSMUSG00000041482 (Mm), ENSRNOG00000038784 (Rn) |
Entrez Gene | 63895 (Hs), 667742 (Mm), 307380 (Rn) |
Human Protein Atlas | ENSG00000154864 (Hs) |
KEGG Gene | hsa:63895 (Hs), mmu:667742 (Mm), rno:307380 (Rn) |
OMIM | 613629 (Hs) |
Orphanet | ORPHA332055 (Hs) |
Pharos | Q9H5I5 (Hs) |
RefSeq Nucleotide | NM_022068 (Hs), NM_001039485 (Mm) |
RefSeq Protein | NP_071351 (Hs), NP_001034574 (Mm) |
UniProtKB | Q9H5I5 (Hs), Q8CD54 (Mm) |
Wikipedia | PIEZO2 (Hs) |
Functional Characteristics | |
Mechano-activated |
Piezo channels: Piezo2. Last modified on 15/04/2019. Accessed on 13/01/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetomalariapharmacology.org/GRAC/ObjectDisplayForward?objectId=2946.