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bromodomain and PHD finger containing 3

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Target id: 2731

Nomenclature: bromodomain and PHD finger containing 3

Family: Non-enzymatic BRD containing proteins

Contents:

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 1205 6p21.31 BRPF3 bromodomain and PHD finger containing 3
Mouse - 1204 17 A3.3 Brpf3 bromodomain and PHD finger containing, 3
Rat - 1199 20p12 Brpf3 bromodomain and PHD finger containing, 3
Previous and Unofficial Names Click here for help
bromodomain and PHD finger containing, 3 | bromodomain and PHD finger containing
Database Links Click here for help
Alphafold Q9ULD4 (Hs)
CATH/Gene3D 1.20.920.10, 3.30.40.10
ChEMBL Target CHEMBL3108644 (Hs)
Ensembl Gene ENSG00000096070 (Hs), ENSMUSG00000063952 (Mm), ENSRNOG00000028641 (Rn)
Entrez Gene 27154 (Hs), 268936 (Mm), 309647 (Rn)
Human Protein Atlas ENSG00000096070 (Hs)
KEGG Gene hsa:27154 (Hs), mmu:268936 (Mm), rno:309647 (Rn)
Pharos Q9ULD4 (Hs)
RefSeq Nucleotide NM_015695 (Hs), NM_001081315 (Mm), NM_001107615 (Rn)
RefSeq Protein NP_056510 (Hs), NP_001074784 (Mm), NP_001101085 (Rn)
UniProtKB Q9ULD4 (Hs)
Wikipedia BRPF3 (Hs)
Other Binding Ligands
Key to terms and symbols Click column headers to sort
Ligand Sp. Action Value Parameter Reference
NI-57 Small molecule or natural product Click here for species-specific activity table Ligand has a PDB structure Hs Binding 6.4 pKd 1
⤷ pKd 6.4 (Kd 4.08x10-7 M) [1]
OF-1 Small molecule or natural product Click here for species-specific activity table Ligand has a PDB structure Hs Binding 5.6 pKd 2
⤷ pKd 5.6 (Kd 2.4x10-6 M) [2]
Description: By isothermal titration calorimetry.

References

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1. SGC. NI-57 – a chemical probe for BRPF bromodomains. Accessed on 15/07/2015. Modified on 04/08/2023. thesgc.org, https://www.thesgc.org/chemical-probes/NI-57

2. SGC. OF-1 A chemical probe for BRPF bromodomains. Accessed on 05/04/2017. Modified on 04/08/2023. SGC, https://www.thesgc.org/chemical-probes/OF-1

How to cite this page

Non-enzymatic BRD containing proteins: bromodomain and PHD finger containing 3. Last modified on 05/04/2017. Accessed on 19/09/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetomalariapharmacology.org/GRAC/ObjectDisplayForward?objectId=2731.