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Cytokine receptor common β subunit

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Target id: 2306

Nomenclature: Cytokine receptor common β subunit

Family: IL-3 receptor family

Quaternary Structure: Complexes
Interleukin-3 receptor
Interleukin-5 receptor
Granulocyte macrophage colony-stimulating factor receptor
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 897 22q12.3 CSF2RB colony stimulating factor 2 receptor subunit beta
Mouse 1 896 15 37.36 cM Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Rat - - 7q34 Csf2rb colony stimulating factor 2 receptor subunit beta
Previous and Unofficial Names Click here for help
CD131 | GM-CSF/IL-3/IL-5 receptor common beta subunit | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | colony stimulating factor 2 receptor | colony stimulating factor 2 receptor beta common subunit
Database Links Click here for help
Alphafold
CATH/Gene3D
ChEMBL Target
DrugBank Target
Ensembl Gene
Human Protein Atlas
Pharos
UniProtKB
Wikipedia
Immunopharmacology Comments
This a signal transducing protein subunit shared by the functional receptor heterodimers for the cytokines IL-3, IL-5 and GM-CSF, with each receptor having a unique ligand binding alpha subunit.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling

How to cite this page

IL-3 receptor family: Cytokine receptor common β subunit. Last modified on 22/03/2017. Accessed on 21/02/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetomalariapharmacology.org/GRAC/ObjectDisplayForward?objectId=2306.