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Interleukin 20 receptor, β subunit

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Target id: 1730

Nomenclature: Interleukin 20 receptor, β subunit

Family: IL-10 receptor family

Contents:

Quaternary Structure: Complexes
Interleukin-20 receptor
Interleukin-22α1/20β heteromer
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 311 3q22.3 IL20RB interleukin 20 receptor subunit beta
Mouse - - Il20rb interleukin 20 receptor beta
Rat - - Il20rb interleukin 20 receptor subunit beta
Previous and Unofficial Names Click here for help
DIRS1 | FNDC6 | IL-20R2 | fibronectin type III domain containing 6 | interleukin 20 receptor beta
Database Links Click here for help
Alphafold Q6UXL0 (Hs)
CATH/Gene3D 2.60.40.10
Ensembl Gene ENSG00000174564 (Hs), ENSMUSG00000044244 (Mm), ENSRNOG00000023214 (Rn)
Entrez Gene 53833 (Hs), 213208 (Mm), 501043 (Rn)
Human Protein Atlas ENSG00000174564 (Hs)
KEGG Gene hsa:53833 (Hs), mmu:213208 (Mm), rno:501043 (Rn)
OMIM 605621 (Hs)
Pharos Q6UXL0 (Hs)
UniProtKB Q6UXL0 (Hs)
Wikipedia IL20RB (Hs)
Immunopharmacology Comments
Interleukin 20 receptor, β subunit is a component of the functional receptor heterodimers for interleukins 19, 20 and 24.
Immuno Process Associations
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 6 GO processes
GO:0004896 cytokine receptor activity IBA
GO:0019221 cytokine-mediated signaling pathway IBA
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GO:0032689 negative regulation of type II interferon production IEA
GO:0032703 negative regulation of interleukin-2 production IEA
GO:0032733 positive regulation of interleukin-10 production IEA
GO:0032753 positive regulation of interleukin-4 production IEA
Immuno Process:  Inflammation
GO Annotations:  Associated to 2 GO processes, IEA only
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GO:0001808 negative regulation of type IV hypersensitivity IEA
GO:0002437 inflammatory response to antigenic stimulus IEA
Immuno Process:  T cell (activation)
GO Annotations:  Associated to 3 GO processes, IEA only
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GO:0001808 negative regulation of type IV hypersensitivity IEA
GO:0042098 T cell proliferation IEA
GO:0042130 negative regulation of T cell proliferation IEA
Immuno Process:  B cell (activation)
GO Annotations:  Associated to 1 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0001808 negative regulation of type IV hypersensitivity IEA
Immuno Process:  Immune regulation
GO Annotations:  Associated to 4 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0001808 negative regulation of type IV hypersensitivity IEA
GO:0002765 immune response-inhibiting signal transduction IEA
GO:0042130 negative regulation of T cell proliferation IEA
GO:0043029 T cell homeostasis IEA
Immuno Process:  Chemotaxis & migration
GO Annotations:  Associated to 1 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0042130 negative regulation of T cell proliferation IEA
Immuno Process:  Cellular signalling
GO Annotations:  Associated to 3 GO processes, IEA only
click arrow to show/hide IEA associations
GO:0002765 immune response-inhibiting signal transduction IEA
GO:0042098 T cell proliferation IEA
GO:0042130 negative regulation of T cell proliferation IEA

How to cite this page

IL-10 receptor family: Interleukin 20 receptor, β subunit. Last modified on 06/04/2017. Accessed on 21/03/2023. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetomalariapharmacology.org/GRAC/ObjectDisplayForward?objectId=1730.