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protein arginine methyltransferase 7

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Target id: 1258

Nomenclature: protein arginine methyltransferase 7

Abbreviated Name: PRMT7

Family: 2.1.1.- Protein arginine N-methyltransferases

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 692 16q22.1 PRMT7 protein arginine methyltransferase 7
Mouse - 692 8 D3 Prmt7 protein arginine N-methyltransferase 7
Rat - 693 19q12 Prmt7 protein arginine methyltransferase 7
Previous and Unofficial Names Click here for help
[Myelin basic protein]-arginine N-methyltransferase PRMT7
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
Enzyme Reaction Click here for help
EC Number:
EC Number:

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Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
DS-437 Small molecule or natural product Primary target of this compound Click here for species-specific activity table Hs Inhibition 5.2 pIC50 1
pIC50 5.2 (IC50 6x10-6 M) [1]


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1. Smil D, Eram MS, Li F, Kennedy S, Szewczyk MM, Brown PJ, Barsyte-Lovejoy D, Arrowsmith CH, Vedadi M, Schapira M. (2015) Discovery of a Dual PRMT5-PRMT7 Inhibitor. ACS Med Chem Lett, 6 (4): 408-12. [PMID:25893041]

How to cite this page

2.1.1.- Protein arginine N-methyltransferases: protein arginine methyltransferase 7 . Last modified on 13/08/2015. Accessed on 13/07/2024. IUPHAR/BPS Guide to PHARMACOLOGY,