Gene and Protein Information
class A G protein-coupled receptor
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	7	588	12p13	GPR162	G protein-coupled receptor 162
Mouse	7	588	6 59.17 cM	Gpr162	G protein-coupled receptor 162
Rat	7	575	4q42	Gpr162	G protein-coupled receptor 162

Previous and Unofficial Names

GRCA

Database Links
Specialist databases
GPCRdb	gp162_human (Hs), gp162_mouse (Mm)
Other databases
Alphafold	Q16538 (Hs), Q3UN16 (Mm)
ChEMBL Target	CHEMBL4523871 (Hs)
Ensembl Gene	ENSG00000250510 (Hs), ENSMUSG00000038390 (Mm), ENSRNOG00000016143 (Rn)
Entrez Gene	27239 (Hs), 14788 (Mm), 362436 (Rn)
Human Protein Atlas	ENSG00000250510 (Hs)
KEGG Gene	hsa:27239 (Hs), mmu:14788 (Mm), rno:362436 (Rn)
Pharos	Q16538 (Hs)
RefSeq Nucleotide	NM_019858 (Hs), NM_013533 (Mm), NM_001108646 (Rn)
RefSeq Protein	NP_062832 (Hs), NP_038561 (Mm), NP_001102116 (Rn)
UniProtKB	Q16538 (Hs), Q3UN16 (Mm)
Wikipedia	GPR162 (Hs)

Tissue Distribution
Central nervous system, lung, sexual organs Species:  Human Technique:  Expressed sequence tag References:  2

Expression Datasets
Show »« Hide Log average relative transcript abundance in mouse tissues measured by qPCR from Regard, J.B., Sato, I.T., and Coughlin, S.R. (2008). Anatomical profiling of G protein-coupled receptor expression. Cell, 135(3): 561-71. [PMID:18984166] [Raw data: website] There should be a chart of expression data here, you may need to enable JavaScript!

Biologically Significant Variants
Type:  Single nucleotide polymorphism Species:  Human Amino acid change:  G450R Global MAF (%):  3 Subpopulation MAF (%):  AFR|AMR|ASN|EUR: 6|2|3|3 Minor allele count:  A=0.032/70 Comment on frequency:  Low frequency (<10% in all tested populations) SNP accession:  rs148895065 Validation:  Frequency
Type:  Single nucleotide polymorphism Species:  Human Amino acid change:  R459G Global MAF (%):  15 Subpopulation MAF (%):  AFR|AMR|EUR: 1|23|30 Minor allele count:  G=0.146/319 SNP accession:  VAR_049407, rs11612427 Validation:  1000 Genomes, HapMap, Frequency References:  1