abaloparatide   Click here for help

GtoPdb Ligand ID: 8299

Synonyms: BA058 | Tymlos®
Approved drug
abaloparatide is an approved drug (FDA (2017))
Compound class: Peptide or derivative
Comment: Abaloparatide is a synthetic analogue of the 34 amino-terminal residues of human parathyroid hormone-related protein (PTHrP) [1]. Compare this to the approved drug teriparatide which is a synthetic analogue of human parathyroid hormone (PTH). Abaloparatide and teriparatide are synthetic peptides that help grow and strengthen bone.
Peptide Sequence Click here for help
AVSEHQLLHDKGKSIQDLRRRELLEKLLAKLHTA
Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Ala-Lys-Leu-His-Thr-Ala
Chemical Modification
Ala29 is methyl-Ala, C-terminal Ala is amidated.