[D-Tyr6,β-Ala11,N-Me-Ala13,Nle14]bombesin-(6-14)   Click here for help

GtoPdb Ligand ID: 11434

Compound class: Peptide or derivative
Comment: This is a stabilised gastrin-releasing peptide receptor (BB2 receptor) agonist that is >4000-fold selective for the BB2 receptor over the other two bombesin receptors [1].
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Peptide Sequence Click here for help
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D-Tyr-Gln-Trp-Ala-Val-βAla-His-N-Me-Ala-Nle
Chemical Modification
Residue one is D-tyrosine; residue 11 is β-alanine; residue 13 is N-Me-Ala; residue 14 is norleucine