C12-iE-DAP   Click here for help

GtoPdb Ligand ID: 9508

Comment: C12-iE-DAP is an acylated derivative of the dipeptide γ-iE-DAP. It is present in the peptidoglycan (PGN) of Gram-negative bacilli and select Gram-positive bacteria. It is a NOD1 ligand.
1. Lee J, Tattoli I, Wojtal KA, Vavricka SR, Philpott DJ, Girardin SE. (2009)
pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling.
J Biol Chem, 284 (35): 23818-29. [PMID:19570976]