Ca2+   Click here for help

GtoPdb Ligand ID: 707

Synonyms: calcium ion
Compound class: Inorganic
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1. Barfod ET, Moore AL, Lidofsky SD. (2001)
Cloning and functional expression of a liver isoform of the small conductance Ca2+-activated K+ channel SK3.
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Intracellular calcium strongly potentiates agonist-activated TRPC5 channels.
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Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A).
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Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid.
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Polycystin-L is a calcium-regulated cation channel permeable to calcium ions.
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Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Galphas stimulation.
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Ca2+-activated K+ channels in human leukemic Jurkat T cells. Molecular cloning, biochemical and functional characterization.
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Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits.
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An electrophysiological investigation of the properties of a murine recombinant 5-HT3 receptor stably expressed in HEK 293 cells.
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10. Grissmer S, Nguyen AN, Cahalan MD. (1993)
Calcium-activated potassium channels in resting and activated human T lymphocytes. Expression levels, calcium dependence, ion selectivity, and pharmacology.
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TRPC5 is a Ca2+-activated channel functionally coupled to Ca2+-selective ion channels.
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12. Hill J, Howlett A, Klein C. (2000)
Nitric oxide selectively inhibits adenylyl cyclase isoforms 5 and 6.
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13. Hirschberg B, Maylie J, Adelman JP, Marrion NV. (1998)
Gating of recombinant small-conductance Ca-activated K+ channels by calcium.
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TRPM5 is a voltage-modulated and Ca(2+)-activated monovalent selective cation channel.
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Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels.
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Role of aspartate 298 in mouse 5-HT3A receptor gating and modulation by extracellular Ca2+.
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A human intermediate conductance calcium-activated potassium channel.
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Isolation and characterization of a novel cardiac adenylylcyclase cDNA.
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19. Iwami G, Kawabe J, Ebina T, Cannon PJ, Homcy CJ, Ishikawa Y. (1995)
Regulation of adenylyl cyclase by protein kinase A.
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20. Joiner WJ, Tang MD, Wang LY, Dworetzky SI, Boissard CG, Gan L, Gribkoff VK, Kaczmarek LK. (1998)
Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits.
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21. Joiner WJ, Wang LY, Tang MD, Kaczmarek LK. (1997)
hSK4, a member of a novel subfamily of calcium-activated potassium channels.
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22. Kohler M, Hirschberg B, Bond CT, Kinzie JM, Marrion NV, Maylie J, Adelman JP. (1996)
Small-conductance, calcium-activated potassium channels from mammalian brain.
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23. Koulen P, Cai Y, Geng L, Maeda Y, Nishimura S, Witzgall R, Ehrlich BE, Somlo S. (2002)
Polycystin-2 is an intracellular calcium release channel.
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24. Lai HL, Lin TH, Kao YY, Lin WJ, Hwang MJ, Chern Y. (1999)
The N terminus domain of type VI adenylyl cyclase mediates its inhibition by protein kinase C.
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25. Liu D, Liman ER. (2003)
Intracellular Ca2+ and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5.
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26. Logsdon NJ, Kang J, Togo JA, Christian EP, Aiyar J. (1997)
A novel gene, hKCa4, encodes the calcium-activated potassium channel in human T lymphocytes.
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27. Mochizuki S, Miyake A, Furuichi K. (1999)
Ion permeation properties of a cloned human 5-HT3 receptor transiently expressed in HEK 293 cells.
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28. Nagy E, Rigby WF. (1995)
Glyceraldehyde-3-phosphate dehydrogenase selectively binds AU-rich RNA in the NAD(+)-binding region (Rossmann fold).
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29. Niemeyer MI, Lummis SC. (2001)
The role of the agonist binding site in Ca(2+) inhibition of the recombinant 5-HT(3A) receptor.
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30. Nilius B, Mahieu F, Prenen J, Janssens A, Owsianik G, Vennekens R, Voets T. (2006)
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate.
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31. Nilius B, Prenen J, Janssens A, Voets T, Droogmans G. (2004)
Decavanadate modulates gating of TRPM4 cation channels.
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32. Nilius B, Prenen J, Tang J, Wang C, Owsianik G, Janssens A, Voets T, Zhu MX. (2005)
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4.
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33. Paulais M, Lachheb S, Teulon J. (2006)
A Na+- and Cl- -activated K+ channel in the thick ascending limb of mouse kidney.
J Gen Physiol, 127 (2): 205-15. [PMID:16446508]
34. Pedarzani P, McCutcheon JE, Rogge G, Jensen BS, Christophersen P, Hougaard C, Strøbaek D, Stocker M. (2005)
Specific enhancement of SK channel activity selectively potentiates the afterhyperpolarizing current I(AHP) and modulates the firing properties of hippocampal pyramidal neurons.
J Biol Chem, 280 (50): 41404-11. [PMID:16239218]
35. Pi M, Faber P, Ekema G, Jackson PD, Ting A, Wang N, Fontilla-Poole M, Mays RW, Brunden KR, Harrington JJ et al.. (2005)
Identification of a novel extracellular cation-sensing G-protein-coupled receptor.
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36. Riccardi D, Park J, Lee WS, Gamba G, Brown EM, Hebert SC. (1995)
Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor.
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37. Syme CA, Gerlach AC, Singh AK, Devor DC. (2000)
Pharmacological activation of cloned intermediate- and small-conductance Ca(2+)-activated K(+) channels.
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38. Takezawa R, Cheng H, Beck A, Ishikawa J, Launay P, Kubota H, Kinet JP, Fleig A, Yamada T, Penner R. (2006)
A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity.
Mol Pharmacol, 69 (4): 1413-20. [PMID:16407466]
39. Taussig R, Tang WJ, Hepler JR, Gilman AG. (1994)
Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.
J Biol Chem, 269 (8): 6093-100. [PMID:8119955]
40. Trattnig SM, Gasiorek A, Deeb TZ, Ortiz EJ, Moss SJ, Jensen AA, Davies PA. (2016)
Copper and protons directly activate the zinc-activated channel.
Biochem Pharmacol, 103: 109-17. [PMID:26872532]
41. Ullrich ND, Voets T, Prenen J, Vennekens R, Talavera K, Droogmans G, Nilius B. (2005)
Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice.
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42. Wittekindt OH, Visan V, Tomita H, Imtiaz F, Gargus JJ, Lehmann-Horn F, Grissmer S, Morris-Rosendahl DJ. (2004)
An apamin- and scyllatoxin-insensitive isoform of the human SK3 channel.
Mol Pharmacol, 65 (3): 788-801. [PMID:14978258]
43. Xia XM, Fakler B, Rivard A, Wayman G, Johnson-Pais T, Keen JE, Ishii T, Hirschberg B, Bond CT, Lutsenko S et al.. (1998)
Mechanism of calcium gating in small-conductance calcium-activated potassium channels.
Nature, 395 (6701): 503-7. [PMID:9774106]
44. Yoshimura M, Cooper DM. (1992)
Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.
Proc Natl Acad Sci USA, 89 (15): 6716-20. [PMID:1379717]