panitumumab   Click here for help

GtoPdb Ligand ID: 6883

Synonyms: ABX-EGF | ABX-EGF Mab | Vectibix®
Approved drug
panitumumab is an approved drug (FDA (2006), EMA (2007))
Compound class: Antibody
Comment: Binds to and competitively inhibits the activity of the epidermal growth factor receptor.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Foon KA, Yang XD, Weiner LM, Belldegrun AS, Figlin RA, Crawford J, Rowinsky EK, Dutcher JP, Vogelzang NJ, Gollub J et al.. (2004)
Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody.
Int J Radiat Oncol Biol Phys, 58 (3): 984-90. [PMID:14967460]