- Guide to PHARMACOLOGY
Synonyms: AT-Resolvin D1 | AT-RvD1
Compound class: Metabolite or derivative
Comment: This is a 17R-epimer of resolvin D1 (RvD1) that is a useful research tool as it shows delayed enzymatic degradation compared to the endogenous 17S-epimer.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Bang S, Yoo S, Yang TJ, Cho H, Hwang SW. (2012)
17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception.
Br J Pharmacol, 165 (3): 683-92. [PMID:21718307]
2. Krishnamoorthy S, Recchiuti A, Chiang N, Fredman G, Serhan CN. (2012)
Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs.
Am J Pathol, 180 (5): 2018-27. [PMID:22449948]