peptidoglycan

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Ligands
peptidoglycan

GtoPdb Ligand ID: 5044

Abbreviated name: PGN

Synonyms: murein

Compound class: Natural product or derivative

Comment: Peptidoglycan is a polymer of sugars and amino acids forming a crystal lattice structure

Summary
Biological activity
References

References
1. Schwandner R, Dziarski R, Wesche H, Rothe M, Kirschning CJ. (1999) Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J Biol Chem, 274 (25): 17406-9. [PMID:10364168]
2. Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D. (1999) Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J Immunol, 163 (1): 1-5. [PMID:10384090]

References

1. Schwandner R, Dziarski R, Wesche H, Rothe M, Kirschning CJ. (1999)
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2.
J Biol Chem, 274 (25): 17406-9. [PMID:10364168]

2. Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D. (1999)
Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2.
J Immunol, 163 (1): 1-5. [PMID:10384090]