- Guide to PHARMACOLOGY
Synonyms: 3-veratroylveracevine | veratrine
Compound class: Natural product or derivative
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Catterall WA, Morrow CS, Daly JW, Brown GB. (1981)
Binding of batrachotoxinin A 20-alpha-benzoate to a receptor site associated with sodium channels in synaptic nerve ending particles.
J Biol Chem, 256 (17): 8922-7. [PMID:6114956]
2. Farrag KJ, Bhattacharjee A, Docherty RJ. (2008)
A comparison of the effects of veratridine on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in isolated rat dorsal root ganglion neurons.
Pflugers Arch, 455 (5): 929-38. [PMID:17962978]
3. Wang G, Dugas M, Armah BI, Honerjäger P. (1990)
Sodium channel comodification with full activator reveals veratridine reaction dynamics.
Mol Pharmacol, 37 (2): 144-8. [PMID:2154667]
4. Wang SY, Wang GK. (1998)
Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin.
Proc Natl Acad Sci USA, 95 (5): 2653-8. [PMID:9482942]