TamRLX   Click here for help

GtoPdb Ligand ID: 11462

 Ligand is labelled
Compound class: Peptide or derivative
Comment: This is TAMRA labelled relaxin peptide that can be used in fluorescent detection assays such as NanoBRET [1]. The orange-red TAMRA fluorescent dye is added at the N terminus of the A-chain of relaxin. This dimerises with relaxin (B chain) to form H2 relaxin.
Click here for help

Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

✖

View interactive charts of activity data across species
References
1. Hoare BL, Bruell S, Sethi A, Gooley PR, Lew MJ, Hossain MA, Inoue A, Scott DJ, Bathgate RAD. (2019)
Multi-Component Mechanism of H2 Relaxin Binding to RXFP1 through NanoBRET Kinetic Analysis.
iScience, 11: 93-113. [PMID:30594862]