Synonyms: XOMA 052 | XOMA-052
Compound class:
Antibody
Comment: Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
|
Immunopharmacology Comments |
Gevokizumab down-modulates, rather than completely blocks, IL-1β signalling capacity. It has therapeutic potential to treat inflammatory conditions where IL1β is a contributory factor, including type 2 diabetes mellitus, rheumatoid arthritis and cardiovascular disease [2,5-6]. |
Immunopharmacology Disease | |||
Disease | X-Refs | Comment | References |
Uveitis |
Disease Ontology:
DOID:13141 |
Approved therapeutic for uveitis. | |
Uveitis |
Disease Ontology:
DOID:13141 |
Gevokizumab is a FDA and EMA orphan drug for the management of chronic non-infectious uveitis. | 1,7 |