Synonyms: ANB-011 | dostarlimab-gxly | Jemperli® | TSR-042 | WBP-285
dostarlimab is an approved drug (EMA & FDA (2021))
Compound class:
Antibody
Comment: Dostarlimab is a humanized, IgG4κ programmed cell death 1 (PD-1) blocking monoclonal antibody from GlaxoSmithKline.
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Immunopharmacology Comments |
Dostarlimab blocks the inhibitory immune checkpoint interaction between PD-1 and its ligands PD-L1 and PD-L2 to promote an antitumour T-cell response. |