Lys[Z(NO2)]-Val   Click here for help

GtoPdb Ligand ID: 9486

Comment: A side chain modified dipeptide inhibitor of PepT1 (Peptide transporter 1 / SLC15A1) [2].
Click here for help
Selectivity at transporters
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Peptide transporter 2 Hs Inhibitor Inhibition 7.0 pKi - 1,3
pKi 7.0 [1,3]
Peptide transporter 1 Hs Inhibitor Inhibition 5.7 pKi - 2
pKi 5.7 (Ki 2x10-6 M) [2]
Description: Competition assays in Caco-2 cells expressing PEPT1.