ibritumomab tiuxetan   Click here for help

GtoPdb Ligand ID: 6777

Synonyms: IDEC-2B8 | IDEC-Y2B8-yttrium ibritumomab tiuxetan | NSC-715848 | Zevalin®
Approved drug Immunopharmacology Ligand
ibritumomab tiuxetan is an approved drug (FDA (2002), EMA (2004))
Compound class: Antibody
Comment: A monoclonal antibody used as a radioimmunotherapy treatment.
Bioactivity Comments
The labelled antibody shows high affinity and selectivity for its target antigen [1]. We have been unable to find affinity data for the interaction between this antibody and CD20 in any open access article.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD20 (membrane-spanning 4-domains, subfamily A, member 1) Primary target of this compound Hs Antibody Binding - - -