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Ligands
canakinumab
canakinumab
GtoPdb Ligand ID: 6773
Synonyms:
ACZ 885 | ACZ885 | Ilaris®
canakinumab is an
approved drug
(FDA (2009), EMA (2009))
Compound class:
Antibody
Comment:
Canakinumab targets interleukin-1β [
1
].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Summary
Biological activity
Clinical data
References
Immunopharmacology
Selectivity at ligand targets
Key to terms and symbols
Click column headers to sort
Target
Sp.
Type
Action
Value
Parameter
Concentration range (M)
Reference
IL-1β
Hs
Antibody
Binding
10.5
p
K
d
-
3
⤷
p
K
d
10.5 (
K
d
3.5x10
-11
M) [
3
]