CIS43

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Ligands
CIS43

GtoPdb Ligand ID: 11254

Comment: CIS43 is a human monoclonal antibody directed against the P. falciparum circumsporozoite protein (PfCSP) [3]. The structure has not been formally disclosed and has not been curated by IMGT.

The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.

Summary
Biological activity
Clinical data
References
Malaria

Bioactivity Comments
CIS43 has been shown to inhibit liver stage infection in vitro and to confer sterile protection in two different mouse models of malaria infection [3].

Bioactivity Comments

CIS43 has been shown to inhibit liver stage infection in vitro and to confer sterile protection in two different mouse models of malaria infection [3].